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1

Nitrooxymethyl-Substituted Analogues of Rofecoxib: Synthesis and Pharmacological Characterization

Donatella Boschi, Clara Cena, Antonella Di Stilo, Barbara Rolando, Paola Manzini, Roberta Fruttero, Alberto Gasco

Journal:

Chemistry & Biodiversity

Year:

2010

Language:

english

File:

PDF, 185 KB

english, 2010

2

Searching for Balanced Hybrid NO-Donor 1,4-Dihydropyridines with Basic Properties

Donatella Boschi, Giulia Caron, Sonja Visentin, Antonella Di Stilo, Barbara Rolando, Roberta Fruttero, Alberto Gasco

Journal:

Pharmaceutical Research

Year:

2001

Language:

english

File:

PDF, 142 KB

english, 2001

3

Synthesis of NO-Donor Bisphosphonates and Their in-Vitro Action on Bone Resorption

Lazzarato, Loretta, Rolando, Barbara, Lolli, Marco L., Tron, Gian Cesare, Fruttero, Roberta, Gasco, Alberto, Deleide, Guido, Guenther, Harald L.

Journal:

Journal of Medicinal Chemistry

Year:

2005

Language:

english

File:

PDF, 134 KB

english, 2005

4

Phenylsulfonylfuroxans as Modulators of Multidrug-Resistance-Associated Protein-1 and P-Glycoprotein

Fruttero, Roberta, Crosetti, Marco, Chegaev, Konstantin, Guglielmo, Stefano, Gasco, Alberto, Berardi, Francesco, Niso, Mauro, Perrone, Roberto, Panaro, Maria Antonietta, Colabufo, Nicola Antonio

Journal:

Journal of Medicinal Chemistry

Year:

2010

Language:

english

File:

PDF, 1.12 MB

english, 2010

5

Structure-Property Relationships in the Basicity and Lipophilicity of Arylalkylamine Oxides

Giulia Caron, Giuseppe Ermondi, Donatella Boschi, Pierre-Alain Carrupt, Roberta Fruttero, Bernard Testa, Alberto Gasco

Journal:

Helvetica Chimica Acta

Year:

1999

Language:

english

File:

PDF, 112 KB

english, 1999

6

Ionic Partition Diagram of the Zwitterionic Antihistamine Cetirizine

Géraldine Bouchard, Alessandra Pagliara, Georgette Plemper van Balen, Pierre-Alain Carrupt, Bernard Testa, Véronique Gobry, Hubert H. Girault, Giulia Caron, Giuseppe Ermondi, Roberta Fruttero

Journal:

Helvetica Chimica Acta

Year:

2001

Language:

english

File:

PDF, 173 KB

english, 2001

7

Molecular-Dynamics and NMR Investigation of the Property Space of the Zwitterionic Antihistamine Cetirizine

Giuseppe Ermondi, Giulia Caron, Géraldine Bouchard, Georgette Plemper van Balen, Alessandra Pagliara, Teresa Grandi, Pierre-Alain Carrupt, Roberta Fruttero, Bernard Testa

Journal:

Helvetica Chimica Acta

Year:

2001

Language:

english

File:

PDF, 197 KB

english, 2001

8

Potential Histamine H2-Receptor Antagonists: Ranitidine Analogues Containing “Semicarbazono Equivalent” Groups

Giovanni Sorba, Roberta Fruttero, Rosella Calvino, Alberto Gasco, Marco Orsetti

Journal:

Archiv der Pharmazie

Year:

1984

Language:

english

File:

PDF, 305 KB

english, 1984

9

α1-Adrenoceptor Blocking Activity of Some Ring-open Analogues of Prazosin

Donatella Boschi, Antonella Di Stilo, Roberta Fruttero, Claudio Medana, Giovanni Sorba, Alberto Gasco

Journal:

Archiv der Pharmazie

Year:

1994

Language:

english

File:

PDF, 505 KB

english, 1994

10

The Furoxan System: Design of Selective Nitric Oxide (NO) Donor Inhibitors of COX-2 Endowed with Anti-Aggregatory and Vasodilating Activities

Erika Del Grosso, Donatella Boschi, Loretta Lazzarato, Clara Cena, Antonella Di Stilo, Roberta Fruttero, Stefano Moro, Alberto Gasco

Journal:

Chemistry & Biodiversity

Year:

2005

Language:

english

File:

PDF, 330 KB

english, 2005

11

Nitrooxymethyl-Substituted Analogues of Celecoxib: Synthesis and Pharmacological Characterization

Donatella Boschi, Loretta Lazzarato, Barbara Rolando, Andrea Filieri, Clara Cena, Antonella Di Stilo, Roberta Fruttero, Alberto Gasco

Journal:

Chemistry & Biodiversity

Year:

2009

Language:

english

File:

PDF, 198 KB

english, 2009

12

A New Furoxan NO-Donor Rabeprazole Derivative and Related Compounds

Giovanni Sorba, Ubaldina Galli, Clara Cena, Roberta Fruttero, Alberto Gasco, Giuseppina Morini, Maristella Adami, Gabriella Coruzzi, Maria Immacolata Brenciaglia, Francesco Dubini

Journal:

Year:

2003

Language:

english

File:

PDF, 118 KB

english, 2003

13

ChemInform Abstract: Synthesis of New Bicyclic Analogues of Glutamic Acid.

Paola Conti, Clelia Dallanoce, Marco De Amici, Carlo De Micheli, Roberta Fruttero

Journal:

Year:

1999

File:

PDF, 35 KB

1999

14

ChemInform Abstract: Nitroanilines Are the Reduction Products of Benzofuroxan System by Oxyhemoglobin (HbO22+).

Claudio Medana, Sonja Visentin, Giorgio Grosa, Roberta Fruttero, Alberto Gasco

Journal:

Year:

2002

File:

PDF, 28 KB

2002

15

Liposome/Water Lipophilicity: Methods, Information Content, and Pharmaceutical Applications

Georgette Plemper van Balen, Catherine a Marca Martinet, Giulia Caron, Geraldine Bouchard, Marianne Reist, Pierre-Alain Carrupt, Roberta Fruttero, Alberto Gasco, Bernard Testa

Journal:

Year:

2004

File:

PDF, 52 KB

2004

16

A New Class of NO-Donor H3-Antagonists.

Paolo Tosco, Massimo Bertinaria, Antonella Di Stilo, Elisabetta Marini, Barbara Rolando, Giovanni Sorba, Roberta Fruttero, Alberto Gasco

Journal:

Year:

2004

File:

PDF, 134 KB

2004

17

Development of a New Class of Potential Antiatherosclerosis Agents: NO-Donor Antioxidants.

Clara Cena, Donatella Boschi, Gian Cesare Tron, Kostantin Chegaev, Loretta Lazzarato, Antonella Di Stilo, Manuela Aragno, Roberta Fruttero, Alberto Gasco

Journal:

Year:

2005

File:

PDF, 15 KB

2005

18

ChemInform Abstract: A New Series of Amodiaquine Analogues (I) Modified in the Basic Side Chain with in vitro Antileishmanial and Antiplasmodial Activity.

Stefano Guglielmo, Massimo Bertinaria, Barbara Rolando, Marco Crosetti, Roberta Fruttero, Vanessa Yardley, Simon L. Croft, Alberto Gasco

Journal:

Year:

2010

File:

PDF, 22 KB

2010

19

ChemInform Abstract: 1,2,5-Oxadiazole Analogues of Leflunomide and Related Compounds.

Marta Giorgis, Marco Lucio Lolli, Barbara Rolando, Angela Rao, Paolo Tosco, Shilpi Chaurasia, Domenica Marabello, Roberta Fruttero, Alberto Gasco

Journal:

Year:

2011

File:

PDF, 66 KB

2011

20

ChemInform Abstract: Synthesis and in vitro Antimicrobial Activities of New (Cyano-NNO-azoxy) Pyrazole Derivatives.

Donatella Boschi, Stefano Guglielmo, Stefania Aiello, Giulia Morace, Elisa Borghi, Roberta Fruttero

Journal:

Year:

2011

Language:

english

File:

PDF, 26 KB

english, 2011

21

Synthesis, chiral HPLC resolution and configuration assignment of 1-phenylglyceryl trinitrate stereomers

Konstantin Chegaev, Loretta Lazzarato, Gian Cesare Tron, Domenica Marabello, Antonella Di Stilo, Clara Cena, Roberta Fruttero, Alberto Gasco, Nicolas Vanthuyne, Christian Roussel

Journal:

Year:

2006

Language:

english

File:

PDF, 157 KB

english, 2006

22

Amphiphilic NO-Donor Antioxidants

Konstantin Chegaev, Loretta Lazzarato, Barbara Rolando, Elisabetta Marini, Gloria V. Lopez, Massimo Bertinaria, Antonella Di Stilo, Roberta Fruttero, Alberto Gasco

Journal:

Year:

2007

Language:

english

File:

PDF, 162 KB

english, 2007

23

Structure–Antioxidant Activity Relationships in a Series of NO-Donor Phenols

Paolo Tosco, Elisabetta Marini, Barbara Rolando, Loretta Lazzarato, Clara Cena, Massimo Bertinaria, Roberta Fruttero, Marianne Reist, Pierre-Alain Carrupt, Alberto Gasco

Journal:

Year:

2008

Language:

english

File:

PDF, 325 KB

english, 2008

24

Amphiphilic NO-Donor Antioxidants

Konstantin Chegaev, Loretta Lazzarato, Barbara Rolando, Elisabetta Marini, Gloria V. Lopez, Massimo Bertinaria, Antonella Di Stilo, Roberta Fruttero, Alberto Gasco

Journal:

Year:

2008

File:

PDF, 69 KB

2008

25

Multitarget Drugs: Synthesis and Preliminary Pharmacological Characterization of Zileuton Analogues Endowed with Dual 5-LO Inhibitor and NO-Dependent Activities

Donatella Boschi, Marta Giorgis, Clara Cena, Naveen Chandra Talniya, Antonella Di Stilo, Giuseppina Morini, Gabriella Coruzzi, Elena Guaita, Roberta Fruttero, Alberto Gasco

Journal:

Year:

2010

Language:

english

File:

PDF, 300 KB

english, 2010

26

Nitrooxyacyl Derivatives of Salicylic Acid: Aspirin-Like Molecules that Covalently Inactivate Cyclooxygenase-1

Prof. Dr. Clara Cena, Dr. Paolo Tosco, Dr. Elisabetta Marini, Dr. Loretta Lazzarato, Prof. Dr. Marco Piccinini, Dr. Cristina Ramondetti, Dr. Elisa Lupino, Prof. Roberta Fruttero, Prof. Alberto Gasco

Journal:

Year:

2011

Language:

english

File:

PDF, 672 KB

english, 2011

27

Synthesis and anti-Helicobacter pylori properties of NO-donor/metronidazole hybrids and related compounds

Massimo Bertinaria, Ubaldina Galli, Giovanni Sorba, Roberta Fruttero, Alberto Gasco, Maria Immacolata Brenciaglia, Maria Maddalena Scaltrito, Francesco Dubini

Journal:

Drug Development Research

Year:

2003

Language:

english

File:

PDF, 167 KB

english, 2003

28

The Lipophilicity Behavior of Three Catechol-O-methyltransferase (COMT) Inhibitors and Simple Analogues

Laura Novaroli, Geraldine Bouchard Doulakas, Marianne Reist, Barbara Rolando, Roberta Fruttero, Alberto Gasco, Pierre-Alain Carrupt

Journal:

Helvetica Chimica Acta

Year:

2006

Language:

english

File:

PDF, 141 KB

english, 2006

29

Physicochemical Profiling of Sartans: A Detailed Study of Ionization Constants and Distribution Coefficients

Paolo Tosco, Barbara Rolando, Roberta Fruttero, Yveline Henchoz, Sophie Martel, Pierre-Alain Carrupt, Alberto Gasco

Journal:

Helvetica Chimica Acta

Year:

2008

Language:

english

File:

PDF, 337 KB

english, 2008

30

Unsymmetrically substituted furoxans. Part 19. Methyl and phenylfuroxansulfonic acids and related sulfonamides

Konstantin Chegaev, Barbara Rolando, Stefano Guglielmo, Roberta Fruttero, Alberto Gasco

Journal:

Journal of Heterocyclic Chemistry

Year:

2009

Language:

english

File:

PDF, 117 KB

english, 2009

31

A structural study of Tryller's and Schmitz's compounds and related substances

Roberta Fruttero, Bruno Ferrarotti, Alberto Gasco, Gianluca Calestani, Corrado Rizzoli

Journal:

European Journal of Organic Chemistry

Year:

1988

Language:

english

File:

PDF, 660 KB

english, 1988

32

Unsymmetrically substituted furoxans, XII. Phenylfuroxancarboxylic acids and their derivatives

Roberta Fruttero, Bruno Ferrarotti, Anna Serafino, Alberto Gasco

Journal:

European Journal of Organic Chemistry

Year:

1990

Language:

english

File:

PDF, 345 KB

english, 1990

33

Unsymmetrically substituted furoxans, XIII. Phenylfuroxancarbaldehydes and related compounds

Andrea Marcello Gasco, Roberta Fruttero, Giovanni Sorba, Alberto Gasco

Journal:

European Journal of Organic Chemistry

Year:

1991

Language:

english

File:

PDF, 278 KB

english, 1991

34

Unsymmetrically Substituted Furoxans, XIV. Synthesis and Structure of a Trimer of the Furoxan System with High Vasodilator and Platelet Antiaggregatory Activity

Andrea Marcello Gasco, Antonella Di Stilo, Roberta Fruttero, Giovanni Sorba, Alberto Gasco, Piera Sabatino

Journal:

European Journal of Organic Chemistry

Year:

1993

Language:

english

File:

PDF, 313 KB

english, 1993

35

Liposome/water lipophilicity: Methods, information content, and pharmaceutical applications

Georgette Plemper van Balen, Catherine a Marca Martinet, Giulia Caron, Géraldine Bouchard, Marianne Reist, Pierre-Alain Carrupt, Roberta Fruttero, Alberto Gasco, Bernard Testa

Journal:

Medicinal Research Reviews

Year:

2004

Language:

english

File:

PDF, 382 KB

english, 2004

36

Deuterium isotope effects on oxygen-17 chemical shifts

Silvio Aime, Enrica Santucci, Roberta Fruttero

Journal:

Magnetic Resonance in Chemistry

Year:

1986

Language:

english

File:

PDF, 282 KB

english, 1986

37

Dipole moments and electron distribution of furoxans and furazans

Václav Všetečka, Roberta Fruttero, Alberto Gasco, Otto Exner

Journal:

Journal of Molecular Structure

Year:

1994

Language:

english

File:

PDF, 503 KB

english, 1994

38

Acyclic analogs of classical H2-antagonists: synthesis and activity of dialkylamioalkyl substituted ethers and oximes

Giovanni Sorba, Roberta Fruttero, Alberto Gasco, Marco Orsetti

Journal:

European Journal of Medicinal Chemistry

Year:

1987

Language:

english

File:

PDF, 501 KB

english, 1987

39

Furoxan analogues of the histamine H3-receptor antagonist imoproxifan and related furazan derivatives

Paolo Tosco, Massimo Bertinaria, Antonella Di Stilo, Clara Cena, Giovanni Sorba, Roberta Fruttero, Alberto Gasco

Journal:

Bioorganic & Medicinal Chemistry

Year:

2005

Language:

english

File:

PDF, 297 KB

english, 2005

40

Novel antioxidant agents deriving from molecular combination of Vitamin C and NO-donor moieties

Clara Cena, Konstantin Chegaev, Silvia Balbo, Loretta Lazzarato, Barbara Rolando, Marta Giorgis, Elisabetta Marini, Roberta Fruttero, Alberto Gasco

Journal:

Bioorganic & Medicinal Chemistry

Year:

2008

Language:

english

File:

PDF, 188 KB

english, 2008

41

Synthesis and preliminary pharmacological characterisation of a new class of nitrogen-containing bisphosphonates (N-BPs)

Marco L. Lolli, Barbara Rolando, Paolo Tosco, Shilpi Chaurasia, Antonella Di Stilo, Loretta Lazzarato, Eva Gorassini, Riccardo Ferracini, Simonetta Oliaro-Bosso, Roberta Fruttero, Alberto Gasco

Journal:

Bioorganic & Medicinal Chemistry

Year:

2010

Language:

english

File:

PDF, 673 KB

english, 2010

42

Development of a new class of potential antiatherosclerosis agents: NO-donor antioxidants

Clara Cena, Donatella Boschi, Gian Cesare Tron, Kostantin Chegaev, Loretta Lazzarato, Antonella Di Stilo, Manuela Aragno, Roberta Fruttero, Alberto Gasco

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2004

Language:

english

File:

PDF, 274 KB

english, 2004

43

Synthesis and in vitro antimicrobial activities of new (cyano-NNO-azoxy)pyrazole derivatives

Donatella Boschi, Stefano Guglielmo, Stefania Aiello, Giulia Morace, Elisa Borghi, Roberta Fruttero

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2011

Language:

english

File:

PDF, 1013 KB

english, 2011

44

A new series of amodiaquine analogues modified in the basic side chain with in vitro antileishmanial and antiplasmodial activity

Stefano Guglielmo, Massimo Bertinaria, Barbara Rolando, Marco Crosetti, Roberta Fruttero, Vanessa Yardley, Simon L. Croft, Alberto Gasco

Journal:

European Journal of Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 475 KB

english, 2009

45

Evidence of self-protonation on the electrodic reduction mechanism of an anti-Helicobacter pylori metronidazole isotere

Janesmar C.M. Cavalcanti, Natália V. Oliveira, Maria Aline B.F. de Moura, Roberta Fruttero, Massimo Bertinaria, Marilia O.F. Goulart

Journal:

Journal of Electroanalytical Chemistry

Year:

2004

Language:

english

File:

PDF, 400 KB

english, 2004

46

The relationship between redox potentials and substituent constants in biologically active arylazoxy compounds

Francine Santos de Paula, Écio Matias Sales, Maura Vallaro, Roberta Fruttero, Marília O.F. Goulart

Journal:

Journal of Electroanalytical Chemistry

Year:

2005

Language:

english

File:

PDF, 307 KB

english, 2005

47

Reversed-phase high-performance liquid chromatographic study of the lipophilicity of a series of analogues of the antibiotic “calvatic acid”

Rosella Calvino, Roberta Fruttero, Alberto Gasco

Journal:

Journal of Chromatography A

Year:

1991

Language:

english

File:

PDF, 385 KB

english, 1991

48

Electrochemical studies of biologically active arylazoxy compounds. The relationship between redox potentials and molluscicidal activities

Francine Santos de Paula, Alessandra G Cioletti, Jorge F da Silva Filho, Antônio Euzébio G Santana, Aldenir F dos Santos, Marı́lia O.F Goulart, Maura Vallaro, Roberta Fruttero

Journal:

Journal of Electroanalytical Chemistry

Year:

2003

Language:

english

File:

PDF, 264 KB

english, 2003

49

Michael addition of Grignard reagents to tetraethyl ethenylidenebisphosphonate

Marco L Lolli, Loretta Lazzarato, Antonella Di Stilo, Roberta Fruttero, Alberto Gasco

Journal:

Journal of Organometallic Chemistry

Year:

2002

Language:

english

File:

PDF, 366 KB

english, 2002

50

Synthesis of new bicyclic analogues of glutamic acid

Paola Conti, Clelia Dallanoce, Marco De Amici, Carlo De Micheli, Roberta Fruttero

Journal:

Year:

1999

Language:

english

File:

PDF, 649 KB

english, 1999